What Drug Increases Digoxin Toxicity
04122020 Some drugs can affect your blood levels of other drugs you take which may increase side effects or make the medications less effective. 01082019 Saquinavir Invirase and ritonavir Norvir increase the amount of digoxin in the body and may cause digoxin toxicity. Image Result For Digoxin In Heart Failure Pharmacology Nursing Nerdy Nurse Nurses Notes Some coadministered drugs such as macrolides and cardiovascular drugs especially amiodarone can cause digoxin overdose through pharmacokinetic interactions. What drug increases digoxin toxicity . The mechanism most often implicated is inhibition of P-glycoprotein of which digoxin is a substrate. Actions might result in rapid increases in digoxin blood concentrations and related toxic symptoms. Erythromycin clarithromycin and tetracyclines - May increase digoxin levels. Than acute intoxication7 Digoxin pharmacology Digoxin increases intracellular calcium in myocardial cells indirectly by inhibiting the sodiumpotassium pump...